The duo will play in the back three alongside Alex Lewington, meaning James O'Connor and Eamonn Sheridan make up the centres.

Shane Geraghty moves back to fly-half with Ian Humphreys named as a replacement.

John Yapp, David Paice and Jamie Hagan make up the front row with George Skivington and Nic Rouse in the second row.

Kieran Low, Blair Cowan and Ofisa Treviranus are named in the back row while Darren Allinson continues at scrum-half in the absence of the suspended Tomas O'Leary.

Irish director of rugby Brian Smith said: “We want to finish this block of Premiership games well and go to Exeter and put in the type of performance that has seen us win away at Saracens and Wasps.

"Exeter are similar to us in the fact that they will fight for everything, however, we have prepared well this week and will go to Sandy Park with a winning intent.”

London Irish team to face Exeter Chiefs: 15. Topsy Ojo; 14. Alex Lewington; 13.Eamonn Sheridan; 12. James O’Connor; 11. Marland Yarde; 10. Shane Geraghty; 9. Darren Allinson; 1. John Yapp; 2. David Paice; 3. Jamie Hagan; 4. George Skivington (Captain); 5. Nic Rouse; 6. Kieran Low; 7. Blair Cowan; 8. Ofisa Treviranus.

Replacements: 16. Mike Mayhew; 17. Matt Parr; 18. Leo Halavatau; 19. Jebb Sinclair; 20. Ian Gough; 21. Gerard Ellis; 22. Ian Humphreys; 23. Ed Hoadley.