15 Academy talents, including six from the Under-21s, have been released following Reading's relegation from the Championship.
12 first-team players, six of which were on loan, departed as the club prepare for a first season in the third tier since 2002.
These include the likes of Lucas Joao, Luke Southwood and Shane Long.
Among the Academy graduates include the likes of Nahum Melvin-Lambert, Kian Leavy, Claudio Osorio and Rashawn Scott, all of which have made first-team appearances for the club.
Lui Bradbury, Ethan Burnett and Josh Green all move on without breaking into the first-team.
Coniah Boyce-Clarke, who made his first-team debut in the final match of last season, has been offered a new three-year deal. Defenders John Clarke, Matt Carson and Jeriel Dorsett has also been offered extensions.
Hamid Abdel-Salam, Adrian Akande, Harvey Collins, Matt Rowley and Michael Stickland have all had extensions triggered on their current deals.
David Nyarko, Ryley Campbell, Kyle Daniel-Spray, Harrison Furlong, Louis Hutchings, Troy Murray, Zion Nditi and Aston Greaver have all been released from the club's Under-18s side.
Harvey Maudner, Jacob Borgnis, Tom Norcott, Caylan Vickers, Jeremiah Okine-Peters and Basil Tuma are among the teenagers to have signed first professional contracts for the club.
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