Iconic striker Shane Long makes his first start for the club since his emotional return over the summer.
The Irishman, who played 10 minutes in last week's defeat to Blackpool, comes in for Yakou Meite- who is presumed to be injured.
The remainder of the team is unchanged from the side that lost at Bloomfield Road, with it looking a likely 4-2-3-1 formation.
Full team: Lumley; Hoilett;Β Yiadom; Holmes; McIntyre; Guinness-Walker; Fornah; Hendrick; Ince; Ejaria; Long
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β Reading FC (@ReadingFC) August 6, 2022
One change - it's a first start since returning for Shane Long.
17-year-old forward Basil Tuma is involved in a matchday squad for the first time.#REACAR pic.twitter.com/PuckLNnKQE
There is also just one change for the visitors as Curtis Nelson replaces the suspended Perry Ng.
Former Royal Andy Rinomhota returns to play against the side where he spent almost a decade after his summer switch to Wales.
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